Paper Title
Secretory Structures, Histochemical And Phytochemical Compounds In The Physialis Angulata Leaves (Solanaceae) As A Prospect Of Medicinal Development

Physialis angulata L. is the one of Solanaceae families which can be used as traditional medicine. In Indonesia, particularly in North Kalimantan Province, the leaves of P. angulata are used by Dayak Kenyah tribe as herbal medicine to reduces inflammation, relieves pain, prevents ulcers, and reduces fever. This study aims to identify and analyze the secretory structure, histochemical and phytochemical content in the Physialis angulata leaves. Observation of secretory structures by using light microscope showed that P. angulata leaves have the secretory structures in the form of idioblast cells and capitate glandular trichomes. Idioblast cells spread in epidermis. Capitate glandular trichomes on the upper and lower leaf surfaces. Histochemical test indicated that the idioblast cells contains terpenoids compounds. Capitate glandular trichomes has one stalk cell and four head cells containing alkaloid, terpenoid and lipophilic compounds. The GC-MS analysis of the samples shows that thirty phytochemicals were identified in the chloroform extract. Commonly, the components belong to terpenes, including sesquiterpenes, diterpenes and triterpenes. In addition, it is found a group of compounds in the form of esters, fatty acids, alcohols, and steroids. Phytol compounds is one of the main components of the terpenes that has been found. The methanolic extract of the sample was subjected to GC-MS analysis. Thirty-five phytochemicals were identified which include sesquiterpenes, diterpenes, triterpenes, fatty acids, alcohols, and steroids compounds. Those compounds assumed to serve as the infection drugs, so it is possible for drug development in health. In conclusion, the secretory structures were found possible to be used in the development of drug compounds through invitro culture. Key words - Medicinal plants, Physialis angulata, phyto-compounds, Solanaceae