Paper Title
Cellulose Acetate/Peg/Hydroxyapatite Blended Membranes For Dialysis Operation
Abstract
The purpose of this research is to prepare cellulose acetate (CA) based membranes for hemodialysis. It is intended to blend hydroxyapatite (HA) with CA in the presence of polyethylene glycol (PEG). The blended membranes were tested for the effectiveness in dialysis application. Later contact angle and pure water flux of blended membranes were determined to investigate the alterations in CA/PEG matrix after HA addition. Surface morphology of CA/PEG/HA blended membranes was studied using SEM, AFM, FTIR. The results revealed effective and homogeneous blending of CA, PEG and HA. The blended membranes were also tested for Bovine serum albumin (BSA) rejection and urea clearance in order to view their application in dialysis process. The increase of HA weight % in doped solution improved BSA rejection and Urea clearance up to 96.8% and 55.2 % respectively. Prominently, addition of HA to CA/PEG matrix imparted better compaction, protein absorption and porosity which lead to membranes with enhanced BSA rejection, Urea clearance and hydrophilicity.
Keywords- CA/PEG/HA blended membranes, Hemodialysis, BSA rejection, Urea Clearance.