Paper Title
Biological Assessment of Selected Egyptian Chick Pea Cultivar

Abstract
Chickpea (Cicer arietinum) is a legume of the family Fabaceae, subfamily Faboideae. In Egypt, chickpea seeds are usually consumed at the raw green and tender stage, or in the form of mature dry seeds. Based on the results of chemical analysis of seven Egyptian cultivars, Giza 1 was selected for further biological studies. The extract showed a strong hepatoprotective activity based on the measurement of liver enzymes (AST, ALT and AST), levels of albumen, globulin, total protein and lipid profile (total cholesterol, high density lipoprotein, triglycerides, and low density lipoprotein). In addition, Giza 1 extract showed a moderate cytotoxic activity against nine human cancer cell lines (MCF7, HEP2, HEP2, HCT116, HepG2, PC-3, A-549, HELA and CACO) and a moderate antimicrobial activities. The antioxidative stress was also tested by measuring catalase, reduced glutathione, superoxide dismutase and malondialdehyde levels. The low acute toxicity (up to 2 g/Kg) and low cytotoxicity indicates the safety profile of potential of the extract. Key words- Chickpea; Cicer arietinum; hepatoprotective; antioxidative stress; cytotoxicity; LD50.