Paper Title
A NEW STUDY ON OPTIMIZING CERVICAL CANCER TREATMENT: COMPARATIVE EFFICACY OF 3D-CRT, IMRT AND VMAT

Abstract
This research evaluates the efficiency of three different external radiation treatments: 3D-CRT, IMRT, and VMAT in order to enhance treatment protocols for better management of cervical cancer, focusing on their ability to minimize damage to surrounding tissues and enhance patient safety. Material and Methods: Ten patients, averaging 56 years old and mostly with squamous cell carcinoma, were treated with 3D-CRT radiotherapy from January to December 2023. For dosimetric comparison, IMRT and VMAT plans using CT images with contours were evaluated for dosimetric quality. Results:The study demonstrated that IMRT and VMAT more effectively target the treatment volume and deliver reduced radiation doses to OARs compared to 3D-CRT. IMRT resulted in a rectal dose reduction of 2.51 Gy and a bladder dose reduction of 4.94 Gy, while VMAT achieved reductions of 2.82 Gy for the rectum and 5.05 Gy for the bladder. Both modalities also significantly decreased radiation exposure to the small bowel and exhibited superior conformity to target volumes, thereby minimizing toxicity to adjacent healthy tissues. Conclusion: IMRT and VMAT are two methods for treating cervical cancer. IMRT is best for tumors near critical structures, providing precise radiation while sparing surrounding tissue. It's preferred for higher doses and sensitive organs. VMAT, on the other hand, is ideal for patients who struggle to stay still, as it simplifies planning and delivers high doses quickly. The choice between the two depends on collaboration among the radiation oncologist, medical physicist, patient, and the facility's resources. Keywords - Cervical cancer, 3D-CRT, IMRT, VMAT.