Paper Title
BIOCOMPATIBLE COATINGS ONTO MATERIALS USED IN MEDICAL FIELD

Abstract
Current challenges in biomaterials science consist in obtaining complex multifunctional materials by tissue engineering. During recent years, biomimetic strategy has been considered an ideal solution for growing adherent remineralized layers onto mature enamel affected by sub micrometre erosion and initial carious lesions, whereas problems of secondary effects as marginal leakage, hypersensitivity, weak adhesion over time and secondary caries at the interface between the original enamel and the filling materials were eliminated. Thus, growth of synthetic enamel-like materials with good adhesion and dense interface to the original enamel of teeth has been of high interest. This paper focuses on systematic study of compositional, structural, and nano- to mesoscale morphological changes occurring between 4 and 10 days of biomimetic growth of synthetic HAP and CS-HAP layers grown directly onto demineralized natural enamel by using commercial Emdogain as source of proteins in preparation of extracellular hydrogels through a modified method.Synthesis of multifunctional biomimetic CS-HAP materials could provide highly organized enamel-like structure for teeth remineralization. Keywords - Enamel; Biomimetic growth; Hydroxyapatite.