Paper Title
ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF BULB EXTRACTS FROM SCILLA MARITIMA

Abstract
Abstract - Scilla maritima is widely used for the treatment of dermatological problems, respiratory and vaginal ailments, in the region of Setif. The present study reports the evaluation of antioxidant, antihemolyticand antibacterial activities of bulb extracts (CrE: crude extract, HeE: hexane fraction, EaE: ethyl acetate fraction and AqE: aqueous fraction) from this medicinal plant. Total polyphenols and flavonoids of different extracts were determined and ranged from 60.7 to 168.72 ± 5.89 EAG/g and 5.93 to 11.68 µg EQ/mg, respectively. The antioxidant activity of these extracts was evaluated by several methods. Potent DPPH scavenging activity was exhibited by EaE and AqE (IC50 of 24.77±0.96 and 46.93±1.44µg/ml), and these fractions were either the most active in inhibition of β-carotene oxidation (86.38 and 92.36%). CrE showed a significant chelating activity (IC50= 553.07±51.14 µg/ml).While, EaE displayed the greater reducing power (EC50= 38.5±1.14 µg/ml) and inhibited significantly the hemolysis of red blood cells. Results of antibacterial activity indicate that CrE was bactericidal against Bacillus cereus, but bacteriostatic against Staphylococcus aureus and Proteus mirabilis. However, EaE was bactericidal against these bacterial strains. These results support the use of this species in traditional medicine and could be used where antioxidant and antibacterial are warranted. Keywords - Scilla Maritima, Polyphenols, Antioxidant, Antibacterial Activity.