Paper Title
Survival of Patients with Oesophageal Cancer in Santiago De Cuba in the Period 2016-2020

Abstract
The oesophagus cancer is an aggressive neoplasm and presents a high lethality. Oesophageal cancer is clinically characterized as a late-diagnosed disease, which impairs the prognosis of patients and reduces the therapeutic possibilities for curative purposes. The incidence has increased in the last decades, reaching a global report in 2020 of 604 100 new cases. In Cuba, this cancer went from not appearing among the top ten cancers, to ranks eight and unlike the reports of most western countries where there is an increase of oesophageal adenocarcinoma. Squamous cell carcinoma is the prevalent histological form. The aim of our study was to estimate the probability of survival according to variable of interest. We developed an observational-longitudinal study in the period January 2016 - December 2020. The population was all patients with oesophageal cancer over 18 years old, both sexes. Cancers of the oesophagogastric junction (Siewert I-III) were excluded and a sample of 66 was taken according to histological diagnosis. The Kaplan-Meier method was applied to establish the survival function and it was analyzed in period 2016-2020. Among the most significant results, survival was higher for patients undergoing esophagectomy, being higher in those operated with a transhiatal technique. Likewise, it was higher among patients diagnosed with squamous cell carcinoma. We conclude that the survival of this disease among our patients is very low. Surgery remains the best option and the transhiatal technique showed the best survival indicators. Keywords - Oesophageal Adenocarcinoma, Squamous Cell Oesophagus Cancer, Survival.