Paper Title
Analysis Of GSH Levels In The Lung Exposed To E-Cigarette Smoke On The Mousemodel

Abstract
Electric cigarette, also known as Vape, is a cigarette modification in the form of a liquid-filled device and battery operated. Electric cigarettes containpro pilinglycol, diethyl leneglycol, glycerol, distilled water, flavorings and nicotine solvents or nicotine plus plaster. Which will turn into nitronism when exposed to heat and is toxic to the body. The principle of working electric cigarettes is to change the chemicals contained in liquids into steam. Steam from the heating of the battery will be sucked and flow into the body of the e-cigarette user. This study aimed to analyze pulmonary GSH levels in rats exposed to e-cigarettes. The subjects of the study were 30 male Wistar rats aged 2-3 months, weighing 200-300 grams, healthy conditions. The sample was divided into 5 groups, namely the control group, the group exposed to tobacco cigarettes and the group exposed to electric cigarettes with nicotine levels of 3.6 and 9mg. Exposure to 3 cigarette tobacco cigarettes a day exposure to e-cigarettes 3 times a day for 30 days, with 5 ml. Data on GSH levels were analyzed by Anova test with LSD further testing. The results showed that there were significant differences between GSH levels of rats without exposure to smoke and GSH levels of rats exposed to e-cigarette smoke with the lowest GSH levels in the group with 9 mg of nicotine. Keyword: E-cigarette, GSH, lung