Fabrication of Paper-Based Microfluidics by Microembossing
In recent years, microfluidic paper-based analytical device (µPAD) has been receiving attention because it is simple, inexpensive and power-free for low-cost chemical, biological and environmental detection. Moreover, paper is lightweight, easy to stack, store and transport, biodegradable, biocompatible, good for colorimetric tests, flammable for easy disposal of used paper-based diagnostic devices by incineration, and can be chemically modified. Different methods have been demonstrated to fabricate µPADs such as solid wax printing, craft cutting, photolithography, etc. In this study, we proposed and demonstrated microembossing to fabricate µPADs. The processing parameters like temperature, embossing pressure and embossing time were systematically studied. The results showed that the temperature and embossing time played important roles in fabrication of µPADs. Heavy metal detection was conducted to verify the performance of µPADs as fabricated. Fabrication of µPADs can be completed within 10 seconds.
Keywords - Embossing, Filter Paper, Heavy Metal Detection, Paper-Based Microfluidics, Wax