Paper Title
Enzymes As A Catalyst of Knoevenagel Condensation

Abstract
Knoevenagel condensation is widely used for the synthesis of organic compounds and pharmaceuticals. In this lecture the first example of enzyme-catalysed Knoevenagel reaction of an acetaldehyde providing unsaturated products in organic solvents will be discussed. The novel protocol describes a tandem process combining the enzymatic hydrolysis of vinyl esters followed by Knoevenagel reaction. Index Terms - Knoevenagel condensation,enzyme promiscuity, Hydrolases, biocatalysis.