Paper Title
Comparison Among Immediate Implant Placement Of Fresh Extracted Socket At Pristine Site And Sites Associated With Periapical Pathology: A Systematic Review Of The Latest Evidence

Abstract
Teeth may have lost, through dental disease, trauma, or due to congenital absence. However, usually compromised tooth or roots may still present in patients mouth. Traditionally, before placing dental implant, compromised tooth were removed and sockets were left to heal for several months. Whereas, it is sometimes convenient to place implant into extraction sockets immediately to preserve alveolar bone as well as to shorten treatment time. Objectives:To investigate survival and success rates of placing dental implant in sites of periapical or periodontal infection immediately following tooth extraction, and to test whether or not immediate implantation leads to more biological complications when performed at extraction sockets of teeth associated with periapical pathology compared with teeth without periapical pathology. Materials and Methods: An electronic search has been conducted in PubMed website, Medline database National Library of Medicine, National Institution of Health for articles published among April 2013 to December 2018 by using specific terms. The search methodology was implemented based on PICO formulation. The titles and abstracts from these results were read to identify studies within inclusion criteria. Eligibility criteria included clinical humans studies either randomized or not and excluded any review, case series and case report articles. Only articles in English language was conducted. Results: The initially search strategy yielded 62 articles. Eleven studies were identified within selection criteria, from these articles, three were same cohort group of studies, one review article and one case reports were excluded. The manual search of the reference list of identified articles yielded additional papers. Altogether nine studies were included. Keywords - Immediate implant,infected sites, infected socket, periapical lesion, periodontitis, periodontal lesion, endodontic lesion, pathology.