Paper Title
Antimicrobial Activity of Medicinal Mushroom: Algerian Desert Truffle

Abstract
Tirmania pinoyi (Maire)Malençon is a famous edible fungus in Algeria, well-known for its pleasant flavor and aroma. It is consumed as food and for medicinal properties. The aim of present study is to investigate the antimicrobial activity of T. pinoyi collected from El Bayed in West of Algeria. Soxhlet apparatus was used for extraction with a series of solvents, dichloromethane, chloroform, ethyl acetate and methanol in sequence of increasing of polarity. The results obtained revealed that the nature of solvents had a significant effect on both the antioxidant and antimicrobial activities. The antimicrobial activity of T. pinoyi was evaluated against two Gram-positive and two Gram negative bacteria using agar well diffusion methods. The results showed that the majority of the extracts investigated showed greater activities against the Gram-positive and negative bacteria. Keywords - Desert truffle, Tirmania pinoyi (Maire), Antioxidant activity, Antibacterial activity, DPPH, well diffusion methods