Paper Title
Effect of Ethanol Extract of Houttuyniacordatathunb.On Cholesterol and Lipid Metabolism

Abstract
HouttuyniacordataThunb. (Saururaceae) is used traditionally in Asian countries to treat various disease symptoms.This study was performed to investigate cholesterol and lipid metabolism in vivo of ethanol extract of HouttuyniacordataThunb.(HCE). We elucidated that HCE significantly reduced the body weight gain induced through feeding a high-fat diet to SD rat. The contents of cholesterol and lipid were lower in UDE400 group compare to HF (high fat diet) group in vivo. Contents of TG in the plasma showed to decrease in HCE400 group than garciniacambogia (GCE) group. The treatment of HCE significantly reduced the adipose tissue weight in high-fat (HF) rat. When their adipose and liver tissue morphology was investigated for histochemical staining, the distribution of cell size in the HF group was hypertrophied compared with those from HCE groups. These results suggest that HouttuyniacordataThunb.extract could be useful for prevention or treatment of hypercholesterolmia.