Evaluated of The IL-12 and TNF-α levels in Serum of HCV Iraqi patients
Our study aims at detecting the concentration of IL-12 and tumor necrosis factor(TNF-α) in hepatitis C virus patients in ThiQar province compared to the healthy control.
Sixty-eight patients from Thi Qar were randomly selected, 32 males and 36 females aged 23-76 years with 20 healthy individuals with 12 males and 8 females. And for the period from January to December 2017.
ELISA kit from (Takara, China) was used to measure IL-12 and TNF-α concentration.
The result was a high concentration of IL-12 and tumor necrosis factor(TNF-α)in patients (11.3949 ± 3.93553 ng/ml) and (150.54 ± 64.01ng/ml ) compared to healthy (9.6530 ± 0.74842ng/ml), (78.78 ± 46.79ng/ml) Respectively, and significant difference.
Conclusion: In present study, increase the concentration of IL-12 and TNF-α in patients compared with healthy control.