Paper Title
Formation of Hybrid Polymer/Lipid Membranes on a Crystalline Protein Lattice

Abstract
The present study reports on the formation of planar hybrid polymer/lipid membranes resting on a surface (S-)layer lattice. In this innovative approach hybrid polymer/lipid vesicles were bound to the S-layer lattice and in order to form a hybrid planar layer rupture and fusion was triggered either by 1)β-diketone– Eu3+-ion complex formation or 2) successive application of a Ca2+-solution, lowering the pH, and CHAPS. Method1potentially succeeded for a polymer content of 5% whereas method2resulted in planar hybrid membranes with a polymer content of even 60% and 70%. For the first time, evidence is provided that planar hybrid polymer/lipid membranes varying in their polymer content can be effectively formed on an S-layer lattice. Keywords: Bio-Inspired System, Functional Platform, Lipid, Polymer,S-Layer Protein, Supported Membranes.