Antifungal Activity of Some Novel Thiadiazole Derivatives
The antibiotic resistance which was expedited by the use presume on antimicrobial drugs has been a significant global challenge for public health. In addition to this candidiasis is the most common fungal infection worldwide causing important morbidity and mortality especially in immunocompromised patients. Literature survey uncovers that the various derivatives of thiadiazole have been synthesized for their pharmalogical activities and many of them supported the finding that piperazine derivatives are potent against various microorganism strains.
Index Terms - Antifungal, thiodiazole, piperazine.